NAD+ & Resveratrol
300mg nicotinamide riboside — a direct NAD+ precursor — with 100mg trans-resveratrol from Japanese knotweed. Clearly specified doses, vegan, 2-month supply.
Product details: EUR 49.99 — InStock — SKU INP-NMN-B-IO — GetTested
About this supplement
NAD+ and Nicotinamide Riboside
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every cell of the body. It plays a central role in hundreds of metabolic processes, including the conversion of nutrients into cellular energy through its function in the electron transport chain, and the activity of regulatory proteins including sirtuins and PARPs that depend on NAD+ availability to function. Nicotinamide riboside (NR) is a form of vitamin B3 that serves as a direct precursor to NAD+, incorporated into the NAD+ biosynthesis pathway more efficiently than some other niacin forms. Because NR is a niacin precursor, it carries the established regulatory claim for niacin: it contributes to normal energy-yielding metabolism.
Trans-Resveratrol: The Active Form from a Concentrated Source
Resveratrol is a polyphenolic compound found naturally in grapes, berries, and Japanese knotweed. It exists in two structural forms — cis and trans — of which trans-resveratrol is the biologically active and more stable form. Japanese knotweed (Polygonum cuspidatum) contains among the highest natural concentrations of resveratrol of any plant source, making it the preferred botanical source for supplement-grade resveratrol. TURMERIC NAD+ Resveratrol uses 200mg of Japanese knotweed extract per capsule, delivering 100mg of trans-resveratrol.
The NR and Resveratrol Relationship
The combination of NR and resveratrol reflects a specific mechanistic relationship that has attracted significant scientific attention. Sirtuin proteins — a family of regulatory enzymes involved in multiple cellular processes — require NAD+ to function. Resveratrol has been studied for its interaction with sirtuin proteins, particularly SIRT1. NR supports NAD+ availability; resveratrol interacts with pathways that depend on it. The two compounds operate on related biological mechanisms, which is the scientific basis for their combined formulation.
300mg NR and 100mg Trans-Resveratrol: The Doses That Matter
Both compounds are included at doses consistent with the research literature. Nicotinamide riboside at 300mg per capsule and trans-resveratrol at 100mg per capsule, with every dose clearly on the label.
Frequently asked questions
How many capsules are in the container?
60 capsules, a two month supply at the recommended dose of one capsule per day.
What is nicotinamide riboside (NR)?
Nicotinamide riboside is a form of vitamin B3 (niacin) that serves as a direct precursor to NAD+, a coenzyme involved in hundreds of metabolic processes in the body. Because it is a niacin precursor, it carries the regulatory claim that niacin contributes to normal energy-yielding metabolism.
Why is trans-resveratrol used rather than standard resveratrol?
Resveratrol exists in two structural forms — cis and trans. Trans-resveratrol is the biologically active and more stable form, and is the form used in most resveratrol research. Standard resveratrol supplements may contain a mixture of both forms; this formula uses trans-resveratrol specifically.
Why Japanese knotweed as the source of resveratrol?
Japanese knotweed (Polygonum cuspidatum) contains among the highest natural concentrations of resveratrol of any plant source. It is the preferred botanical source for supplement-grade trans-resveratrol, providing a more concentrated extract than grape or berry-derived sources.
Why are NR and resveratrol combined in one formula?
Sirtuin proteins, a family of regulatory enzymes, require NAD+ to function. Resveratrol has been studied for its interactions with sirtuin proteins, particularly SIRT1. NR supports NAD+ availability as a direct precursor; resveratrol is studied in the context of pathways that depend on NAD+ availability. The combination reflects this specific mechanistic relationship.
Who should not take NAD+ RESVERATROL?
For adults only. Not suitable for children, adolescents, or during pregnancy or breastfeeding. Do not exceed the recommended daily dose. Consult a healthcare professional before use if you are taking medication or have a medical condition.
How should I store it?
In the original sealed packaging, in a dry place away from light at +5 to +25°C.
Customer reviews
5.0/5 (1)
- 5/5 — Bit expensive but one of the better formulas I've found so far